PDF: Immunohistochemical evaluation of the inflammatory response in periodontal disease

Periodontal disease is a chronic inflammatory infectious condition that affects the surrounding and/or supporting tissues of the teeth and, in which, like in other infections, bacteria-host interactions determine the nature of the resulting disease.

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The immune response of the host organism to dental biofilm microorganisms can be either protective, destructive or both, contributing to the wide variety of tissue alterations observed in periodontal disease.

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Numerous studies have demonstrated variations in the number and/or density of lymphocyte subpopulations as well as in the number of plasma cells during different stages of periodontal disease.




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