PDF: Peripheral Ossifying Fibroma ­ A Clinical Report

Localized gingival enlargements are fairly common and typically represent reactive proliferative lesions, rather than true neoplasms (Bhaskar & Levin, 1973; Stablein & Silverglade, 1985; van der Waal, 1991).

Peripheral-Ossifying-Fibroma


Reactive or inflammatory lesions represent more than 90% of histopathologically analyzed gingival biopsies (Bhaskar & Levin; Stablein & Silverglade) and most commonly include diagnoses of pyogenic granuloma, fibrous hyperplasia, peripheral ossifying fibroma and peripheral giant cell granuloma.

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Peripheral ossifying fibroma (POF) has been cited in the literature under various names such as cemento ossifying fibroma, peripheral fibroma with osteogenesis, peripheral odontogenic fibroma, calcifying fibroblastic granuloma etc (Bhaskar & Levin; Walters et al., 2001).

POF is defined as a well demarcated and occasionally encapsulated lesion consisting of fibrous tissue containing variable amounts of mineralized material resembling bone (ossifying fibroma) (Waldrom, 1993).


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