Conventional apexification techniques—whether using long-term calcium hydroxide or apical plugs of MTA—are effective in controlling infection but do not promote continued root maturation.
As a result, affected teeth often remain structurally compromised and at higher risk of fracture.
In this case report, the authors present the regenerative endodontic management of an immature necrotic permanent molar using an intracanal medication of calcium hydroxide followed by MM-MTA as a bioceramic sealing material.
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The clinical and radiographic two-year follow-up highlights progressive apical closure, increased root length, and significant thickening of the canal walls—key indicators supporting the efficacy and biological potential of regenerative endodontic protocols in posterior teeth.
This article provides valuable evidence for clinicians seeking predictable alternatives to traditional apexification, particularly in complex molars where maintaining long-term tooth integrity is essential.
👉 I invite dentists and endodontic clinicians around the world to Access and Read the full article in PDF to explore the complete clinical protocol and detailed radiographic outcomes.

