Local Antimicrobial Therapy in Periodontics: A Review of Scientific Publications (2018–2024)


Ovidental Editorial Team
hola@ovidentalgo.com

Local antimicrobial agents have become integral in the management of periodontal diseases, offering targeted treatment with reduced systemic side effects.

Between 2018 and 2024, several studies have evaluated their efficacy and application.​


Efficacy of Propolis in Chronic Periodontitis

A 2022 study examined the adjunctive use of propolis in non-surgical periodontal therapy for chronic periodontitis patients. 

Propolis, a natural resinous substance, demonstrated significant antimicrobial properties. 

The study concluded that propolis could serve as an effective adjunct to conventional treatments, improving both clinical and microbiological outcomes.


Systemic Antibiotics in Periodontal Therapy

Research published in 2024 explored the role of systemic antibiotics in periodontal therapy.

The study highlighted that antibiotics such as amoxicillin, doxycycline, and metronidazole are frequently used to manage periodontal infections.

It emphasized the importance of professional training in their use to minimize risks and ensure patient safety. 


Local Delivery of Chlorhexidine in Periodontal Maintenance

A study investigated the local delivery of chlorhexidine gluconate in periodontal maintenance patients.

The findings indicated that this method effectively reduced periodontal pathogens and improved clinical parameters, suggesting its utility in long-term periodontal care.​

Comparison of Local Probiotic and Systemic Antibiotic Therapies

A 2025 study compared the benefits of local probiotic therapy versus systemic antibiotic treatment in periodontal disease management.

The research found that local probiotics could be a viable alternative, offering benefits without the drawbacks associated with systemic antibiotics. 


Conclusion

The period between 2018 and 2024 has seen significant advancements in the use of local antimicrobial agents in periodontics.

Studies have demonstrated their efficacy in treating chronic periodontitis, reducing the need for systemic antibiotics, and improving patient outcomes.

Continued research and professional education are essential to optimize these therapies in periodontal practice.

References

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