Faced with patients on oral anticoagulants—whether traditional Vitamin K antagonists like warfarin or direct oral anticoagulants (DOACs)—the historical instinct was often to alter or suspend their medication regimen prior to invasive dental procedures.
However, modern evidence-based dentistry is redefining this clinical approach.
The definitive systematic review, “Management of Patients Receiving Anticoagulation Therapy in Dental Practice: A Systematic Review,” recently published in Healthcare (MDPI), provides a comprehensive analysis of contemporary management protocols.
The study highlights that interrupting or modifying therapeutic anticoagulation often introduces a disproportionate risk of severe thromboembolic complications.
Instead, research strongly supports a conservative, patient-centered framework: maintaining the patient's antithrombotic regimen and utilizing advanced local hemostatic measures (such as tranexamic acid, local sponges, or specialized suturing techniques) to safely control postoperative bleeding.
By combining thorough risk stratification, cross-disciplinary communication with prescribing physicians, and robust clinical protocols, dental professionals can confidently navigate these surgical complexities while prioritizing overall patient well-being.
For clinicians aiming to elevate their everyday evidence-based practice and deliver safe, predictable oral surgery to medically compromised patients, this review is essential reading.
📄 Expand your clinical expertise: Click the link below to access the complete open-access study and download the full PDF version directly from MDPI.

