PDF: Immunohistochemical evaluation of the inflammatory response in periodontal disease

Periodontal disease is a chronic inflammatory infectious condition that affects the surrounding and/or supporting tissues of the teeth and, in which, like in other infections, bacteria-host interactions determine the nature of the resulting disease.

The immune response of the host organism to dental biofilm microorganisms can be either protective, destructive or both, contributing to the wide variety of tissue alterations observed in periodontal disease.

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Numerous studies have demonstrated variations in the number and/or density of lymphocyte subpopulations as well as in the number of plasma cells during different stages of periodontal disease.

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