PDF: Facial lesions caused by renal osteodystrophy in a patient with chronic renal insufficiency: a case report


The kidneys regulate different systems in the human body, being responsible for body metabolite excretion, electrolyte balance and arterial blood pressure regulation, red blood cell secretion, gluco-neogenesis, and vitamin D production.



The final kidney disease stage is called Chronic Renal Insufficiency (CRI), which is characterized by extensive damage as well as a progressive and irreversible loss of the kidney glomerular, tubular and endocrine functions.

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A reduced or absent function of the kidneys can lead to alterations in the function of other body systems, known as Uremic Syndrome. 

Major uremic syndrome manifestations include central and peripheral neurological damage, as well as cardiovascular, skin, ophthalmic, endocrine, gastrointestinal and bone damage.