In PDB, osteoclasts go into overdrive, resorbing too much bone, followed by chaotic, disorganized new bone formation that lacks structural integrity.
Although many individuals remain symptom‑free, the condition can give rise to pain, deformities, fractures, and — in about 17 % of cases — involvement of the jaws, especially the maxilla.
For dentists, Paget’s disease represents a unique crossroad of systemic pathology and oral health.
Radiographically, affected jaws may display characteristic “cotton‑wool” bone patterns, hypercementosis, loss of lamina dura, and root resorption.
Clinically, patients may experience loosening teeth, difficulty in extractions, delayed healing, and higher risk of osteomyelitis.
Understanding the epidemiology, pathogenesis, biochemical markers, and therapeutic options of PDB is thus essential for safe and effective dental care.
This article, “Paget’s disease of bone with special reference to dentistry: An insight”, offers a comprehensive review of the disease — from etiology and systemic features to detailed oral and dental manifestations, radiographic clues, histopathology, and management strategies.
To all dentists around the world: we invite you to read the full article in PDF form and deepen your grasp of this intriguing condition. Expand your knowledge — it could make a difference in patient care.
