Although it predominantly affects adults, pediatric presentations remain exceptionally rare and diagnostically challenging.
The case report “Laugier–Hunziker Syndrome in a Young Girl” published in Malaysian Journal of Medicine and Case Reports (2023) highlights a 10-year-old female who presented with recurrent pigmentation involving the lower lip, oral mucosa, and nails — clinical features that could easily mimic other systemic or syndromic causes of pigmentation.
The report underscores the importance of thorough differential diagnosis to exclude Addison’s disease, Peutz–Jeghers syndrome, and drug-induced pigmentation.
► PDF: Rare Genetic Syndromes and Oral Anomalies: A Comprehensive Review with a New Classification Proposal
Histopathological evaluation confirmed benign melanocytic hyperactivity without malignancy, supporting the diagnosis of LHS.
This pediatric case enriches current literature by emphasizing the need for awareness among dentists and pediatricians, as early identification can prevent unnecessary investigations and reassure parents about the benign nature of the condition.
🌐 Dentists and clinicians worldwide are encouraged to read the complete case report to better understand the clinical spectrum and diagnostic approach of this rare pigmentation disorder in children.

