PDF: Drug therapy during pregnancy: implications for dental practice

Pregnancy is accompanied by various physiological and physical changes, including those found in the cardiovascular, respiratory, gastrointestinal, renal and haematological systems. 

These alterations in the pregnant patient may potentially affect drug pharmacokinetics. Also, pharmacotherapy presents a unique matter due to the potential teratogenic effects of certain drugs.

Although medications prescribed by dentists are generally safe during pregnancy, some modifications may be needed. 

In this article we will discuss the changes in the physiology during pregnancy and its impact on drug therapy.

Specific emphasis will be given to the drugs commonly given by dentists, namely, local anaesthetics, analgesics, antibiotics and sedatives.

The aim of this article is to summarise the physiological changes during pregnancy and their effects on the pharmacokinetics of drugs, as well as review the current recommendations for the use of drugs commonly given by dentists, namely local anaesthetics, analgesics, antimicrobials and sedatives.

Suggests that while the commonly used drugs in dentistry are safe during pregnancy, dentists must carefully evaluate the risks versus the benefits of prescribing or administering any drug to a pregnant patient.

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