This book synthesizes decades of scientific evidence demonstrating how chronic periodontitis extends beyond the oral cavity, influencing—and being influenced by—conditions such as diabetes mellitus, cardiovascular disease, adverse pregnancy outcomes, respiratory disorders, obesity, and immune-mediated diseases.
Designed for clinicians, researchers, and dental students, the text emphasizes a multidisciplinary approach, offering practical frameworks for risk assessment, patient communication, and individualized treatment planning.
Each chapter integrates pathophysiological mechanisms with up-to-date clinical recommendations, helping practitioners better understand the systemic implications of periodontal therapy and the importance of early intervention.
This guide stands out for its clarity, scientific rigor, and strong translational value, making it an essential reference for professionals seeking to elevate their periodontal-systemic decision-making.

